NASDAQ: STOK
Stoke Therapeutics, Inc.
Healthcare · Biotechnology
Market Cap
$1.93B
52w High
$40.22
52w Low
$11.17
P/E
-11.52
Volume
1.95M
Outstanding Shares
62.28M
Price vs Fundamentals
Why The Stock Is Moving
What changed
The stock rose 167.93% over the last year. Revenue declined 83.2% over the trailing twelve months. Operating margin moved from 20.03% to -577.46%. Free cash flow declined 313.44% over the trailing twelve months.
What the market seems to be pricing
The stock is rising despite deteriorating fundamentals and now sits at the 81st percentile of its historical P/S range. This is a momentum-driven move — the market may be front-running a recovery that has not yet appeared in reported numbers.
What would invalidate this read
Operating margin (currently -577.46%) would need to stabilize or improve to justify the move. Revenue is declining 83.2% — a trend reversal in the next report would be the key signal to watch. This read is wrong if the next period shows operating metrics turning the corner. At that point the price would be anticipating real improvement rather than running ahead of it.
Company profile
Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies.
Valuation
Stock splits
No stock splits recorded for this ticker.
Profitability & growth
Analyst consensus
12
Buy
3
Hold
0
Sell
Analyst ratings tend to be lagging indicators. Use as one signal among many.
Earnings
Full quarter-by-quarter history of actuals vs estimates. Switch into compare mode to inspect one metric year-over-year.
Next report
Aug 11, 2026
Q3 FY26 · EPS est -$0.73 · Revenue est $5.19M
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